Low vitamin D status: time to recognize and correct a Wisconsin epidemic

As a result of low dietary intake and sun avoidance, low vitamin D status is endemic in Wisconsin. In a convenience sample of postmenopausal Wisconsin residents, 59% had suboptimal D status. Only recently, the medical community has begun to appreciate that low vitamin D status underlies multiple deleterious health consequences including skeletal fragility, muscle weakness, and a potential multitude of non-skeletal morbidities. At present, a routine recommendation indicates that at least 1000 IU of vitamin D3 (cholecalciferol) daily is indicated, although the true requirement may be greater. This review details vitamin D physiology and the prevalence of low vitamin D status in Wisconsin and elsewhere, and provides approaches to optimizing vitamin D status.