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[131I]metaiodobenzylguanidine treatment of a malignant paraganglioma
J L Baulieu1, D Guilloteau, G Calais
1Service de Médecine Nucléaire, Hôpital Bretonneau, Tours, France.
Abstract:
The bone metastases of a malignant, non-secreting paraganglioma were treated with [131I]metaiodobenzylguanidine (131I-MIBG) over a 10-year period. Initial treatment (131I-MIBG: 9.6 GBq) resulted in a decrease in the number of bone metastases from 16 to 2. At three years, a relapse with primary tumor regrowth and liver metastasis was again treated with 131I-MIBG (22.2 GBq). A decrease in the number of bone metastases and MIBG uptake was again observed.