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Multicenter comparison of the contraceptive ring and patch: a randomized controlled trial.

Mitchell D Creinin¹, Leslie A Meyn, Lynn Borgatta

¹Department of Obstetrics, Gynecology and Reproductive Sciences and Magee-Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213-3180, USA. mcreinin@upmc.edu

Obstetrics and Gynecology

|February 2, 2008

Summary

Women seeking a non-daily hormonal contraceptive preferred the contraceptive ring over the patch. The ring demonstrated higher continuation rates and greater satisfaction compared to the patch.

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Area of Science:

Reproductive Health
Contraception
Hormonal Contraceptives

Background:

Combined hormonal contraceptives are widely used for birth control.
Nondaily combined hormonal contraceptive options include the vaginal ring and the transdermal patch.
Patient preference and adherence are crucial factors in contraceptive method effectiveness.

Purpose of the Study:

To compare the acceptability of the contraceptive ring versus the contraceptive patch.
To evaluate continuation rates as the primary measure of acceptability for nondaily combined hormonal contraceptives.
To assess patient satisfaction and adverse effects associated with the ring and patch.

Main Methods:

A randomized controlled trial involving 500 women interested in nondaily combined hormonal contraception.
Participants were assigned to either the contraceptive ring (n=249) or the contraceptive patch (n=251) for four cycles.
Acceptability and adverse effects were assessed via questionnaire during the fourth cycle.

Main Results:

Contraceptive ring users had significantly higher continuation rates (94.6%) compared to patch users (88.2%).
More ring users (71.0%) planned to continue the method post-study versus patch users (26.5%).
Patch users reported more adverse effects including longer periods, dysmenorrhea, nausea, mood swings, and skin rash, and preferred their oral contraceptive over the patch.

Conclusions:

The contraceptive ring is a more acceptable nondaily combined hormonal contraceptive option than the patch for women satisfied with oral contraceptives.
Higher continuation rates and user preference favor the ring for women seeking alternatives to daily oral pills.
Adverse event profiles differ between the ring and patch, influencing user satisfaction and continuation.