Related Experiment Video
Updated: Jul 7, 2026

04:08
Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
Recurrent ectopic pregnancy in a cesarean scar
Marium G Holland1, Jessica L Bienstock
1Department of Gynecology and Obstetrics, the Johns Hopkins University, Baltimore, MD 21230, USA. mghsmith@yahoo.com
Obstetrics and Gynecology
|February 2, 2008
Summary
Cesarean scar ectopic pregnancy is a rare complication. Early ultrasound can detect this condition, allowing for timely medical or surgical treatment to prevent serious hemorrhage.
Area of Science:
- Reproductive Medicine
- Obstetrics and Gynecology
- Diagnostic Imaging
Background:
- Cesarean scar ectopic pregnancy is a rare but serious complication following cesarean delivery.
- Risk factors include prior uterine surgery, infection, and short intervals between pregnancies.
- Early recognition is crucial to prevent uterine rupture and severe hemorrhage.
Observation:
- A patient with a history of cesarean scar ectopic pregnancy presented with a suspected recurrence at 4 6/7 weeks gestation.
- Initial ultrasound findings were suspicious for cesarean scar ectopic pregnancy.
- Diagnosis was confirmed via repeat ultrasonography at 6 weeks gestation.
Findings:
- The recurrent cesarean scar ectopic pregnancy was successfully treated with methotrexate.
- The pregnancy resolved without any complications.
- Serial ultrasound examinations are recommended if the diagnosis is uncertain.
Implications:
- Cesarean scar ectopic pregnancy should be considered in women with prior cesarean deliveries and early ultrasound findings of a thin lower uterine segment or low implantation.
- Treatment can be medical (e.g., methotrexate) or surgical, depending on the clinical scenario.
- Prompt diagnosis and management are vital for patient safety and preventing catastrophic outcomes.
Related Concept Videos
Clinical Applications of Epidermal Stem Cells
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Healing II: Complications
Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...

