Related Experiment Video
Updated: Jul 7, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Pulmonary synovial sarcoma presenting as a pneumothorax during pregnancy
Emmanuel J Esaka1, Jennifer U Celebrezze, Steven H Golde
1Department of Obstetrics and Gynecology, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA. esakajb@yahoo.com
Background:
Synovial sarcoma is a clinically rare, but morphologically well-defined neoplasm, which accounts for approximately 10% of all malignant soft-tissue tumors. The diagnosis can be established with clinical and imaging evaluations together with immunohistochemical, electron microscopy, and molecular genetic studies.
Case:
We describe a case of primary pulmonary synovial sarcoma presenting as a pneumothorax in a young woman at 34 weeks of gestation. Her persistent symptomatology ultimately led to a video-assisted thoracoscopy and thorascopic decortication. The diagnosis was established by pathology and immunohistochemistry of the cells, which were consistent with primary pulmonary synovial sarcoma.
Conclusion:
Malignancies, even those as uncommon as primary synovial sarcoma, should be considered in the differential diagnosis of pneumothorax during pregnancy.
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