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Cognitive performance in suicidal depressed elderly: preliminary report.

Alexandre Y Dombrovski1, Meryl A Butters, Charles F Reynolds

  • 1Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
|February 2, 2008
PubMed
Summary
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Executive function deficits are linked to suicidal behavior in older adults with depression. Poorer performance on executive function, attention, and memory tests indicates increased suicide risk in this population.

Area of Science:

  • Geriatric Psychiatry
  • Neuropsychology
  • Cognitive Neuroscience

Background:

  • Late-life suicide is a significant public health concern.
  • Executive function deficits are implicated in suicide but are understudied in elderly depressed individuals.

Observation:

  • This case-control study compared 32 suicidal depressed older adults with 32 non-suicidal depressed older adults.
  • Cognitive function was assessed using the Dementia Rating Scale (DRS) and the Executive Interview (EXIT25).

Findings:

  • Suicidal participants demonstrated poorer performance on executive function (EXIT25), overall cognition (DRS total scale), memory, and attention.
  • These cognitive deficits were not attributable to dementia, substance use, medication, or brain injury.

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Implications:

  • Executive function, attention, and memory impairments are associated with suicidal behavior in late-life depression.
  • These findings highlight the importance of cognitive assessment in evaluating suicide risk among older adults with depression.