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Kytococcus schroeteri: a probably underdiagnosed pathogen involved in prosthetic valve endocarditis
Christian Aepinus1, Esther Adolph, Christof von Eiff
1Department of Medical Microbiology, Hygiene and Virology, University of Rostock, Rostock, Germany. christian.aepinus@med.uni-rostock.de
Abstract:
Kytoccoccus schroeteri is an emerging pathogen found mainly in association with prosthetic valve endocarditis. A striking aspect of this species is its resistance to penicillins, including isoxazolylpenicillins, making glycopeptide administration and valve replacement the treatment of choice. We present the case of a 38-year-old female diabetic patient with fever up to 39.1 degrees C for two months. Infection of her prosthetic aortic valve was suspected clinically. Repeated blood cultures revealed growth of K. schroeteri. Transesophageal echocardiography demonstrated a vegetation on the prosthetic aortic valve. Antibiotic treatment with vancomycin, rifampin and gentamicin was started and this regimen led to complete resolution of symptoms and disappearance of the vegetation. It is of particular interest that the patient recovered without further surgical procedures. Since the first description of K. schroeteri in 2002, four cases of endocarditis have been published, suggesting antecedent and continuing underdiagnosis.
Insights
Kytoccoccus schroeteri, a prosthetic valve endocarditis pathogen, can be treated effectively with antibiotics like vancomycin, potentially avoiding surgery. This case highlights the need to recognize this emerging infection.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Cardiology
Background:
- Kytoccoccus schroeteri is an emerging pathogen associated with prosthetic valve endocarditis.
- The species exhibits resistance to penicillins, complicating treatment options.
Observation:
- A 38-year-old diabetic female presented with prolonged fever and suspected prosthetic aortic valve infection.
- Blood cultures confirmed Kytoccoccus schroeteri, and echocardiography revealed a vegetation.
Findings:
- The patient received a combination antibiotic regimen including vancomycin, rifampin, and gentamicin.
- This treatment resulted in complete symptom resolution and vegetation disappearance without surgical intervention.
Implications:
- Successful non-surgical management of Kytoccoccus schroeteri prosthetic valve endocarditis is demonstrated.
- This case suggests potential underdiagnosis of Kytoccoccus schroeteri infections.
- Highlights the efficacy of combination antibiotic therapy in managing resistant pathogens.
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