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Pituitary-dependent hyperadrenocorticism in a cockatoo
Simon R Starkey1, James K Morrisey, Jennifer E Stewart
1Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
Journal of the American Veterinary Medical Association
|February 5, 2008
Summary
This study reports the first confirmed case of pituitary-dependent hyperadrenocorticism in a Moluccan cockatoo. This condition, characterized by hormonal imbalance, should be considered in avian patients presenting with similar clinical signs.
Area of Science:
- Avian endocrinology
- Comparative pathology
- Psittaciformes health
Background:
- Pituitary-dependent hyperadrenocorticism (PDH) is a hormonal disorder typically seen in mammals.
- This case explores PDH in a Moluccan cockatoo (Cacatua moluccensis), a species within the Psittaciformes order.
- The bird presented with coelomic distention, rapid weight gain, polyuria, and polydipsia.
Observation:
- Ultrasonography revealed a pseudohernia containing intestines, pancreas, and reproductive tract.
- Biochemical analysis showed hyperglycemia, hypophosphatemia, elevated bile acids, and AST.
- CBC indicated heterophilia, lymphopenia, and monocytosis; liver biopsy showed hepatic lipidosis.
Findings:
- ACTH stimulation tests were equivocal, complicating diagnosis.
- Histologic evaluation of the pituitary gland confirmed PDH.
- The cockatoo experienced complications post-surgery and was euthanatized.
Implications:
- This is the first confirmed case of PDH in Psittaciformes, expanding the known host range for this endocrine disorder.
- Clinicians should consider PDH in birds exhibiting mammalian-like clinical signs.
- Development of reliable diagnostic tests for avian hyperadrenocorticism is needed, as standard tests may be equivocal.
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