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Related Experiment Video

Updated: Jul 7, 2026

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
09:52

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Published on: March 8, 2013

Lymphatic abnormalities demonstrated by lymphoscintigraphy after lower limb cellulitis.

J K Soo1, T A Bicanic, S Heenan

  • 1Department of Dermatology, St George's Hospital, Blackshaw Road, London SW17 0QT, UK. jsoo@doctors.org.uk

The British Journal of Dermatology
|February 5, 2008
PubMed
Summary

Leg cellulitis often leads to lymphatic damage. This study found that most patients admitted with leg cellulitis have underlying lymphatic abnormalities, suggesting a link between impaired lymph drainage and recurrent infections.

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Last Updated: Jul 7, 2026

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
09:52

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Published on: March 8, 2013

Area of Science:

  • Vascular Medicine
  • Dermatology
  • Lymphology

Background:

  • Cellulitis is a frequent reason for hospital admission.
  • Recurrent cellulitis episodes may damage the lymphatic system.
  • Lymphoedema is a known risk factor for cellulitis, but its prevalence in cellulitis patients is unknown.

Purpose of the Study:

  • To investigate the prevalence of lymphatic abnormalities in patients presenting with lower limb cellulitis.
  • To determine if lymphatic dysfunction is a common issue in this patient group.

Main Methods:

  • Prospective study involving patients admitted with lower limb cellulitis.
  • Clinical examination and lymphoscintigraphy were performed.
  • Analysis of lymph drainage patterns using imaging.

Main Results:

  • Thirty patients participated; fifteen underwent lymphoscintigraphy.
  • Thirteen of fifteen patients (87%) showed abnormal lymphoscintigraphy results.
  • Seven patients (47%) had clinical signs of lymphoedema, with impaired lymph drainage indicated by scans.

Conclusions:

  • Lymphatic abnormalities are a significant and frequently overlooked issue in patients with leg cellulitis.
  • Impaired lymph drainage may contribute to the development or recurrence of cellulitis.
  • Further research is warranted to explore the relationship and management strategies.