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Inflammatory Bowel Disease V: Surgical Management

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
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Risk Factors
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Inflammatory Bowel Disease I: Introduction

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...

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Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...

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Related Experiment Video

Updated: Jul 7, 2026

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium

Published on: May 31, 2024

Pre-pouch ileitis after colectomy in paediatric ulcerative colitis.

Carrie Slatter¹, Safwat Girgis, Hien Huynh

¹Division of Pediatric Gastroenterology, Hepatology and Nutrition, Stollery Children's Hospital, Edmonton, and Department of Pathology, University of Alberta, Edmonton, Alberta, Canada.

Acta Paediatrica (Oslo, Norway : 1992)

|February 5, 2008

Summary

Terminal ileitis can occur in children with ulcerative colitis (UC) after colectomy and ileal pouch anal anastomosis (IPAA). This complication should not rule out a UC diagnosis, even if Crohn

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Murine Ileocolic Bowel Resection with Primary Anastomosis

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

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Last Updated: Jul 7, 2026

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium

A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium

Published on: May 31, 2024

Murine Ileocolic Bowel Resection with Primary Anastomosis

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Area of Science:

Pediatric Gastroenterology
Inflammatory Bowel Disease Research
Surgical Complications

Background:

Colectomy with ileal pouch anal anastomosis (IPAA) offers curative potential for ulcerative colitis (UC).
Terminal ileitis is a rare, poorly documented postoperative complication of IPAA, particularly in pediatric patients.

Observation:

Two pediatric patients with medically refractory UC underwent colectomy with IPAA.
One year post-surgery, both presented with bloody diarrhea and weight loss.
Endoscopic and biopsy findings revealed acute-on-chronic inflammation in the pouch and terminal ileum.

Findings:

The inflammation showed a mixed inflammatory infiltrate without granulomas.
Terminal ileitis developed in pediatric patients following IPAA for UC.
This complication occurred despite efforts to rule out Crohn's disease.

Implications:

Terminal ileitis can occur in children with UC post-IPAA and does not exclude a UC diagnosis.
Further research is crucial to understand the pathogenesis of this uncommon condition.
Clinical management should consider terminal ileitis as a potential complication in pediatric UC patients post-IPAA.