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Negative sequence voltages in spontaneous atrial fibrillation or flutter
Wangden Carson1, Yung-Zu Tseng
1Cardiovascular Laboratory, Cardiovascular Division, Department of Internal Medicine, National Taiwan University Hospital, No.1, Chang-Teh Street, Taipei, Taiwan, ROC 100.
International Journal of Cardiology
|February 5, 2008
Summary
Abnormal P loop inscription direction and slow conduction may explain atrial fibrillation (AF) and flutter (AF) genesis. The heart acts as a biological generator, with P loop abnormalities linked to negative sequence physics.
Area of Science:
- Cardiology
- Biophysics
- Medical Physics
Background:
- The pathophysiology of atrial fibrillation (AF) and atrial flutter (AF) initiation remains unknown.
- This study explores if physics principles, specifically the heart as a biological generator, can explain AF/AF genesis.
- Investigates abnormal inscription direction (AID) or abnormal slow conduction (ASC) of the P loop as potential causes.
Purpose of the Study:
- To investigate the role of P loop abnormalities in the genesis of atrial fibrillation (AF) and atrial flutter (AF).
- To propose a new theory for AF/AF based on physics principles of biological generators.
Main Methods:
- Recorded 160 emergency Frank vectorcardiographic tracings from 55 patients with acute myocardial infarction.
- Analyzed P loop inscription direction (AID) and P loop conduction velocity (ASC).
Main Results:
- Thirty (54%) patients exhibited abnormal P loop inscription direction (AID).
- Seven (13%) patients developed AF/AF, with six having AID and all seven showing atrial enlargement.
- Four of the seven AF/AF patients had abnormal slow conduction (ASC) of the P loop.
Conclusions:
- The heart functions as a biological generator with potential issues analogous to electrical generators.
- P loop abnormalities, including figure-of-eight or clockwise rotation linked to negative sequence physics, are documented.
- A novel theory for AF, AF, and atrial premature contractions is proposed, grounded in negative sequence voltages.
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