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Capsular bag refilling using a new accommodating intraocular lens.

Okihiro Nishi1, Kayo Nishi, Yutaro Nishi

  • 1Nishi Eye Hospital, Osaka, Japan. okihiro@nishi-ganka.or.jp

Journal of Cataract and Refractive Surgery
|February 5, 2008
PubMed
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This study details a novel capsular bag refilling technique using an accommodating intraocular lens (IOL) to prevent silicone leakage and capsule opacification, showing promising results in animal models.

Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Surgical Innovation

Background:

  • Cataract surgery often involves intraocular lens (IOL) implantation.
  • Refilling techniques for capsular bags present challenges with silicone leakage and capsule opacification.
  • Accommodating IOLs offer potential for improved visual function post-surgery.

Purpose of the Study:

  • To describe a novel capsular bag refilling procedure utilizing an accommodating intraocular lens (IOL).
  • To evaluate the efficacy of this technique in preventing silicone polymer leakage.
  • To assess the impact on posterior capsule opacification (PCO).

Main Methods:

  • Development of a disk-shaped anterior foldable silicone accommodating IOL acting as a mechanical barrier.
  • Standard phacoemulsification and aspiration followed by implantation of a posterior accommodating IOL with sharp edges.

Related Experiment Videos

  • Piggybacking an anterior accommodating IOL and injecting silicone polymers between the two IOLs.
  • Optional creation of a continuous curvilinear capsulorhexis (PCCC).

    • Main Results:

    • Experiments in pig and rabbit eyes demonstrated minimal to no silicone leakage.
    • Eyes with a PCCC showed no PCO at 5-8 weeks post-surgery.
    • Eyes without a PCCC exhibited varying degrees of PCO.

    Conclusions:

    • The described capsular bag refilling procedure effectively addresses silicone polymer leakage.
    • The technique, particularly with a PCCC, successfully prevents posterior capsule opacification.
    • This method offers a potential solution for challenges in lens refilling techniques.