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Imaging parameters on third harmonic transmit phasing for tissue harmonic generation.

Che-Chou Shen1, Yu-Chun Wang, Chih-Kuang Yeh

  • 1Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan. choushen@mail.ntust.edu.tw

Ultrasound in Medicine & Biology
|February 5, 2008
PubMed
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Third harmonic (3f0) transmit phasing uses fundamental (f0) and 3f0 signals. Optimizing 3f0 transmit amplitude, aperture size, and using multipulse sequences can improve ultrasound imaging performance despite signal attenuation.

Area of Science:

  • Ultrasound imaging
  • Medical physics
  • Acoustics

Background:

  • Third harmonic (3f0) transmit phasing utilizes fundamental (f0) and 3f0 signals to manipulate tissue harmonic amplitude.
  • Acoustic propagation challenges, including attenuation and phase aberration of the 3f0 signal, degrade 3f0 transmit phasing performance.
  • Transmit parameters like aperture size and signal bandwidth significantly influence 3f0 transmit phasing efficacy.

Purpose of the Study:

  • To investigate the impact of acoustic propagation effects and transmit parameters on third harmonic (3f0) transmit phasing.
  • To identify strategies for optimizing harmonic enhancement and suppression in ultrasound imaging.

Main Methods:

  • Extensive simulations were conducted to analyze the effects of tissue attenuation, phase aberration, and transmit parameters (amplitude, aperture size, bandwidth) on 3f0 transmit phasing.

Related Experiment Videos

  • The study evaluated the influence of spectral leakage on tissue harmonic interference.

    • Main Results:

    • Decreased frequency-difference component magnitude, due to attenuation and aberration, compromises harmonic enhancement and suppression.
    • Increased 3f0 transmit amplitude can compensate for reduced frequency-difference components.
    • A smaller 3f0 transmit aperture improves axial uniformity and harmonic suppression.
    • Spectral leakage interferes with tissue harmonics, reducing 3f0 transmit phasing efficacy.

    Conclusions:

    • Adjustable transmit amplitude, phase, and aperture size for the 3f0 signal are crucial for optimizing clinical performance in 3f0 transmit phasing.
    • Multipulse sequences, such as pulse inversion, are beneficial for mitigating spectral leakage and enhancing 3f0 transmit phasing effectiveness.