Related Experiment Video
Updated: Jul 7, 2026

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
Published on: December 20, 2014
Ureteral obstruction and hydronephrosis in a cat associated with retroperitoneal infarction
1Department of Clinical Veterinary Science, University of Bristol, Langford House, Langford, Bristol, UK. raragni@googlemail.com
Insights
A retroperitoneal mass caused kidney obstruction in a cat, leading to ureteronephrectomy. The cat recovered well, indicating successful surgical intervention for this rare condition.
Area of Science:
- Veterinary Medicine
- Surgical Pathology
Background:
- Routine vaccination revealed an abdominal mass in a 9-month-old cat.
- The mass caused significant enlargement and hydronephrosis of the right kidney.
Observation:
- Radiographs and ultrasonography confirmed severe right kidney hydronephrosis.
- Exploratory surgery identified a retroperitoneal mass obstructing the right ureter.
Findings:
- Histopathology revealed the mass composed of adipose and fibrous tissue with vascular infarction.
- The appearance was consistent with ureteral obstruction due to infarction and fibrosis.
Implications:
- Surgical excision (right ureteronephrectomy) was curative.
- The cat demonstrated a positive clinical outcome 3 months post-surgery.
Abstract:
A 9-month-old cat was presented for routine vaccination before rehoming. Physical examination revealed a palpable mass in the cranial abdomen. The right kidney was severely enlarged (6cmx4cm) on plain abdominal radiographs, and failed to opacify normally during intravenous urography. Ultrasonography demonstrated a hydronephrotic right kidney. During exploratory coeliotomy, a retroperitoneal mass was identified, adherent to the caudal edge of the right kidney, enveloping the ureter and blocking urine outflow. The ureter caudal to the mass was of normal size. Right ureteronephrectomy was performed; the mass was subsequently freed from adhesions to the caudal vena cava and sublumbar muscles and excised. Histopathological examination revealed the mass to be composed of both normal and necrotic adipose tissue and fibrous tissue surrounding the ureter and a thrombosed, recanalised vessel. This appearance was consistent with an area of infarction and fibrosis with obstruction of the ureter. The cat was clinically well 3 months postoperatively.
Related Concept Videos
Acute Kidney Injury II: Pathophysiology
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Urinary Tract Calculi V: Nursing Management
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Disorders of the Urinary System
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Ureters

