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Drug-induced paraparotid fat deposition in patients with HIV: case reports
1Salivary Gland Center, and Division of Oral and Maxillofacial Surgery, Columbia University College of Dental Medicine, 630 West 168th Street, New York City, NY 10032, USA.
Background:
The treatment of patients with HIV is managed effectively with highly active antiretroviral therapy, but complications in the form of a lipodystrophy syndrome (LDS) often develop.
Case Description:
. The authors describe two patients who had bilateral parotid area fatty swellings, which are a manifestation of the fat redistribution seen in LDS. Fat hypertrophy, fat atrophy or both in other regions; dyslipidemia; and glucose abnormalities also were present.
Conclusion And Clinical Implications:
Although the LDS in patients with HIV is recognized visibly by fat redistribution, the syndrome includes dyslipidemia and insulin resistance. Dental visits give dentists the opportunity to recognize HIV-related cervicofacial fat alterations. For appropriate attention, referral to the patient's physician who is managing the HIV is indicated.
