Related Experiment Video
Updated: Jul 7, 2026

Monitoring Dynamic Growth of Retinal Vessels in Oxygen-Induced Retinopathy Mouse Model
Published on: April 2, 2021
Retinopathy of prematurity
Deepak Chawla1, Ramesh Agarwal, Ashok K Deorari
1WHO Collaborating Centre for Training & Research in Newborn Care, Division of Neonatology, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
Insights
Retinopathy of Prematurity (ROP) is a growing concern in India due to improved survival rates in premature infants. Early detection through screening programs is crucial for timely treatment and preventing vision loss.
Area of Science:
- Ophthalmology
- Neonatology
- Public Health
Background:
- Improved survival rates for very low birth weight infants in India have led to an increase in Retinopathy of Prematurity (ROP).
- Prematurity is the primary risk factor for ROP, with other contributing factors including oxygenation issues, blood transfusions, sepsis, and apnea.
- ROP is often asymptomatic in its early stages, necessitating robust screening protocols.
Purpose of the Study:
- To outline a protocol for the screening, diagnosis, and treatment of Retinopathy of Prematurity (ROP).
- To provide guidelines for ophthalmic examinations and necessary interventions for ROP.
- To emphasize the importance of collaboration between ophthalmologists and neonatologists for successful ROP management.
Main Methods:
- The protocol includes descriptions of the various stages of ROP.
- Guidelines cover procedures for pupil dilatation and ophthalmic examination.
- Treatment guidelines are provided for cases requiring intervention.
Main Results:
- The abstract does not contain specific results, but outlines a comprehensive approach to ROP management.
- The protocol aims to facilitate early detection and treatment of ROP.
- Effective management relies on coordinated care between specialists.
Conclusions:
- A structured screening and treatment protocol is essential for managing the rising incidence of ROP in premature infants in India.
- Early detection and intervention are key to preventing severe visual impairment.
- Multidisciplinary collaboration is vital for optimal patient outcomes in ROP care.
Abstract:
With improved survival of very low birth infants in India, Retinopathy of Prematurity (ROP) is emerging as a significant problem. The most important risk factor in the pathogenesis of ROP is prematurity. Other factors like, problems with oxygenation frequent blood transfusions, sepsis and apnea have also been implicated in the causation of ROP. Essentially asymptomatic in the initial stages, a good screening program is essential for the early detection and treatment of this condition. Description of the various stages of ROP has been included in the protocol. Guidelines regarding the procedure of dilatation, ophthalmic examination and treatment (if required) have been provided. Close co-operation between the ophthalmologist and neonatologist is essential for a successful outcome.
Related Concept Videos
Diabetic Retinopathy
The Retina
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

