Kimura's disease--an unusual cause of lymphadenopathy in children
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Updated: Jul 7, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Joe Thomas1, Nambiar Veettil Jayachandran, Pradeep Kumar Shenoy Chandrasekhara
1Department of Rheumatology, Nizam's Institute of Medical Sciences, Panjagutta, 500 082 Hyderabad, Andhra Pradesh, India.
Abstract:
Kimura's disease is a rare inflammatory disorder of unknown cause primarily seen in young Asian males. The disease is characterized by a triad of painless subcutaneous masses in the head or neck region, blood and tissue eosinophilia, and markedly elevated serum immunoglobulin E levels. We describe a 3-year-old Indian boy with Kimura's disease who presented with generalized lymphadenopathy. The diagnosis was based on the characteristic histopathologic findings after surgical excision in conjunction with peripheral eosinophilia and elevated serum immunoglobulin E levels.
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