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Updated: Jul 7, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Atypical case of reversible posterior leucoencephalopathy syndrome associated with puerperal HELLP syndrome

Wei-Xia Peng1, Masako Nakaii, Takashi Matsushima

  • 1Department of Obstetrics and Gynecology, Nippon Medical School Musashikosugi Hospital, 1-396 Kosugi-cho, 211-8533, Kanagawa, 211-8533, Japan.

Archives of Gynecology and Obstetrics
|February 6, 2008
PubMed

Reversible posterior lekoencephalopathy syndrome (RPLS) is usually reversible. However, permanent cerebral damage may result if diagnosis is delayed. White matter edema in the posterior cerebral hemispheres is typical on neuroimaging. A 36-year-old primigravid woman underwent induction of labor due to mild pregnancy-induced hypertension. At 5 h after delivery, she developed eclampsia seizures complicated by hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome. Magnetic resonance imaging showed high-density lesions in anterior regions without any abnormalities in posterior cerebral regions. Cases of postpartum RPLS without involvement of posterior brain regions after eclampsia complicated by HELLP syndrome are very rare. Patients with RPLS do not always show typical manifestations.

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