Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nucleus replacement technologies.

Domagoj Coric1, Praveen V Mummaneni

  • 1Carolina Neurosurgery and Spine Associates, Charlotte, North Carolina 28207, USA. dom@cnsa.com

Journal of Neurosurgery. Spine
|February 6, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparing those Most Satisfied versus Least Satisfied Following Surgery for Cervical Spondylotic Myelopathy: Are there Differences in Baseline Characteristics?

Spine·2026
Same author

Posterior lumbar facet arthroplasty versus fusion for the treatment of spondylolisthesis: 3-year results from the Total Posterior Spine System investigational device exemption study.

Neurosurgical focus·2026
Same author

Introduction. Contemporary spinal arthroplasty.

Neurosurgical focus·2026
Same author

Predictors of long-term myelopathy relief in patients with moderate to severe cervical spondylotic myelopathy following surgery: a Spine CORe™ analysis of QOD data.

Neurosurgical focus·2026
Same author

Is patient satisfaction static at 5 years after surgery for cervical spondylotic myelopathy? A Spine CORe™ analysis of QOD data.

Neurosurgical focus·2026
Same author

What are minimal clinically important differences for patient-reported outcome measures after surgery for cervical spondylotic myelopathy? A 5-year Spine CORe™ analysis of QOD data.

Neurosurgical focus·2026
Same journal

Multilevel stand-alone lateral lumbar interbody fusion: radiographic and clinical outcomes.

Journal of neurosurgery. Spine·2026
Same journal

Is cervicothoracic ossification of the posterior longitudinal ligament a distinct clinicoradiological variant? A critical analysis of neurological recovery predictors.

Journal of neurosurgery. Spine·2026
Same journal

Does preoperative depression predict return to sport and exercise after degenerative spine surgery?

Journal of neurosurgery. Spine·2026
Same journal

Photodynamic diagnosis using 5-aminolevulinic acid in surgery for spinal cord astrocytic tumors: a propensity score-matched comparison with brain tumors.

Journal of neurosurgery. Spine·2026
Same journal

Editorial. Rethinking spinal cord gliomas: beyond the intracranial paradigm.

Journal of neurosurgery. Spine·2026
Same journal

Oncological and neurological outcomes after parent rootlet resection in functionally critical spinal schwannomas: a retrospective multicenter comparative study.

Journal of neurosurgery. Spine·2026
See all related articles

Nucleus replacement is an investigational, less invasive treatment for lumbar degenerative disc disease (DDD). Early results are encouraging, but more research is needed to confirm its effectiveness and ideal uses.

Area of Science:

  • Spinal Surgery
  • Biomedical Engineering
  • Orthopedics

Background:

  • Symptomatic lumbar degenerative disc disease (DDD) affects many patients.
  • Traditional treatments include fusion and total disc replacement.
  • Nucleus replacement presents a less invasive surgical option.

Purpose of the Study:

  • To classify nucleus replacement devices.
  • To discuss potential indications for nucleus replacement.
  • To review the evolution and current investigational status of these devices.

Main Methods:

  • Review of nucleus replacement device history and evolution.
  • Functional categorization of devices into elastomeric and mechanical types.
  • Discussion of a proposed classification scheme.

Related Experiment Videos

Main Results:

  • Nucleus replacement devices are investigational, with several in US trials.
  • Devices are categorized as elastomeric or mechanical.
  • Early clinical outcomes are promising.

Conclusions:

  • Nucleus replacement is an emerging, less invasive treatment for lumbar DDD.
  • Further high-quality clinical trials are necessary.
  • Determining optimal indications and efficacy requires robust prospective studies.