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Published on: January 19, 2019
Incidence of seizures in the acute phase of stroke: a population-based study
Jerzy P Szaflarski1, Angela Y Rackley, Dawn O Kleindorfer
1Department of Neurology and the Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267-0525, USA. jerzy.szaflarski@uc.edu
Purpose:
The incidence of seizures within 24 h of acute stroke has not been studied extensively. We aimed to establish the incidence of acute poststroke seizures in a biracial cohort and to determine whether acute seizure occurrence differs by race/ethnicity, stroke subtype, and/or stroke localization.
Methods:
We identified all stroke cases between July 1993 and June 1994 and in 1999 within the population of the Greater Cincinnati metropolitan region. Patients with a prior history of seizures/epilepsy were excluded from analysis.
Results:
A total of 6044 strokes without a history of seizure(s) were identified; 190 (3.1%) had seizures within the first 24 h of stroke onset. Of ICH/SAH patients, 8.4% had a seizure within the first 24 h of stroke onset (p
Discussion:
The overall incidence of acute seizures after stroke was 3.1%, with a higher incidence seen in hemorrhagic stroke, younger patients, and those presenting with higher prestroke Rankin scores. Acute seizures were associated with a higher mortality at 30 days after stroke.
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