Related Experiment Video
Updated: Jul 7, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
Cognitive and educational deficits in children born extremely preterm
Peter J Anderson1, Lex W Doyle
1Department of Psychology, The University of Melbourne, The Royal Women's Hospital, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia. peterja@unimelb.edu.au
Extremely preterm (EP) children face significant neurodevelopmental challenges, including cognitive and behavioral issues. However, many EP infants achieve better outcomes, influenced by genetic, perinatal, and social factors.
Area of Science:
- Neonatal research
- Developmental pediatrics
- Neuroscience
Background:
- Children born very preterm have increased neurobehavioral impairment risks.
- Limited research exists on outcomes for extremely preterm (EP) infants (<26 weeks gestation or <750g birth weight).
Purpose of the Study:
- To review the literature on the developmental, cognitive, educational, and behavioral outcomes of EP children.
- To identify factors influencing the variability in outcomes for EP children.
Main Methods:
- Literature review of studies on extremely preterm infants.
- Analysis of outcomes including early development, intellectual functioning, cognitive skills, educational attainment, and emotional/behavioral functioning.
Main Results:
- A significant proportion of EP children experience major developmental delays, cognitive impairments, learning disabilities, and behavioral problems.
- A considerable number of EP children, however, do not exhibit major impairments, indicating variable outcomes.
Conclusions:
- EP children and their families face substantial challenges.
- Variability in EP child outcomes is associated with genetic (e.g., gender), perinatal (e.g., brain injury, bronchopulmonary dysplasia), and social-environmental (e.g., social risk, parenting) factors.
Related Concept Videos
Information Processing Approach
The Nativist Approach
Learning Disabilities
Dyslexia
Dyslexia is a...
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Language and Cognition
Intellectual Disability

