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Analysis of adenovirus VA RNAI structure and stability using compensatory base pair modifications

Veronica K Coventry1, Graeme L Conn

  • 1Faculty of Life Sciences, The University of Manchester, Manchester, M1 7DN, UK.

Nucleic Acids Research
|February 6, 2008
PubMed
Summary

Adenovirus VA RNA(I) structure was studied using mutations and melting profiles. The apical stem is an autonomous domain crucial for PKR inhibition, essential for viral protein expression.

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