Related Experiment Video
Updated: Jul 7, 2026

Ultrasonic-Assisted Preparation of Biodiesel Products from Vegetable Oils
Published on: April 19, 2024
Neem oil poisoning.
Ramchandra K Dhongade1, Sandeep G Kavade, Rushikesh S Damle
1Sant Dnyaneshwar Medical Education and Research Center, Pune, Maharashtra, India.
Neem oil poisoning is rare in children, causing severe seizures and metabolic acidosis. This case highlights potential long-term neurological issues like vision and hearing problems, and ataxia.
Area of Science:
- Toxicology
- Pediatric Neurology
- Environmental Health
Background:
- Neem oil, a natural pesticide, is widely used but can be toxic if ingested.
- Accidental poisoning in children is a significant concern, necessitating awareness of potential health impacts.
Purpose of the Study:
- To document an unusual case of neem oil poisoning in a pediatric patient.
- To describe the clinical presentation, management, and neurological sequelae of neem oil toxicity.
Main Methods:
- Case report detailing the clinical course of a 5-year-old child.
- Review of symptoms including refractory seizures and metabolic acidosis.
- Assessment of neurological deficits, including auditory, visual, and motor disturbances.
Main Results:
- The child presented with severe, difficult-to-treat seizures and metabolic acidosis.
- Following initial recovery, the patient developed persistent neurological deficits.
- Observed sequelae included auditory disturbances, visual disturbances, and ataxia.
Conclusions:
- Neem oil poisoning can lead to severe acute symptoms and significant long-term neurological complications in children.
- Early recognition and management are crucial, but late-onset neurological deficits underscore the severity of this toxicity.
- This case emphasizes the need for caution in the use and storage of neem oil around children.
Related Concept Videos
Prevention of Further Absorption of Poison
Pharmaceutical Poisoning: Treatment Strategies
Anticholinesterase Agents: Poisoning and Treatment
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is slower than the...
Pharmaceutical Poisoning: Potential Scenarios
Physical Properties of Amines
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
