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Related Experiment Video

Updated: Jul 7, 2026

An Aptamer-based Sensor for Unchelated Gadolinium(III)

An Aptamer-based Sensor for Unchelated Gadolinium(III)

Published on: January 9, 2017

Gadolinium for hysterosalpingography.

James E Silberzweig¹, Azita S Khorsandi, Megan Caldon

¹Department of Radiology, 4th Floor, St. Luke's-Roosevelt Hospital Center, 1000 Tenth Avenue, New York, NY 10019, USA. jsilberz@chpnet.org

The Journal of Reproductive Medicine

|February 7, 2008

Summary

This summary is machine-generated.

Gadolinium hysterosalpingography offers a safe and effective alternative for patients with iodinated contrast hypersensitivity. This study shows diagnostic value and good outcomes for gadolinium contrast in hysterosalpingography procedures.

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Last Updated: Jul 7, 2026

An Aptamer-based Sensor for Unchelated Gadolinium(III)

An Aptamer-based Sensor for Unchelated Gadolinium(III)

Published on: January 9, 2017

Synthesis of 68Ga Core-doped Iron Oxide Nanoparticles for Dual Positron Emission Tomography /(T1)Magnetic Resonance Imaging

Synthesis of ⁶⁸Ga Core-doped Iron Oxide Nanoparticles for Dual Positron Emission Tomography /(T₁)Magnetic Resonance Imaging

Published on: November 20, 2018

Area of Science:

Radiology
Gynecologic Imaging
Contrast Media Research

Background:

Hysterosalpingography (HSG) traditionally uses iodinated contrast media.
Iodinated contrast media pose a risk of hypersensitivity reactions in certain patients.
Alternative contrast agents are needed for HSG in at-risk populations.

Purpose of the Study:

To assess gadolinium-based contrast agents as a safe alternative for HSG.
To evaluate diagnostic quality, safety, and clinical outcomes of gadolinium HSG.
To determine the utility of gadolinium contrast in patients with hypersensitivity risk.

Main Methods:

Retrospective review of 3,616 HSG examinations (March 2003-March 2006).
Gadolinium contrast used for HSG in patients with known hypersensitivity risk.
Analysis of diagnostic quality, adverse events, and pregnancy outcomes.

Main Results:

Successful diagnostic quality HSG achieved in 11 patients using gadolinium without adverse reactions.
Gadolinium contrast opacification density was lower than with iodinated contrast.
Two of eight eligible patients (patent tubes, not on oral contraceptives) conceived within six months post-procedure.

Conclusions:

Gadolinium contrast hysterosalpingography is diagnostically valuable.
Gadolinium HSG is a safe alternative for patients at high risk of iodinated contrast hypersensitivity.
Gadolinium HSG demonstrates potential clinical utility and safety in specific patient groups.