Related Experiment Videos
Translating the Diabetes Prevention Program into an urban medically underserved community: a nonrandomized
Miriam C Seidel1, Robert O Powell, Janice C Zgibor
1University of Pittsburgh Medical Center, Braddock, Pennsylvania, USA. seidelmc@upmc.edu
Diabetes Care
|February 7, 2008
Summary
A community-based lifestyle intervention effectively reduced type 2 diabetes and cardiovascular disease risk in urban adults with metabolic syndrome. Improvements in weight and metabolic health were sustained for at least six months.
Area of Science:
- Public Health
- Preventive Medicine
- Metabolic Syndrome Research
Background:
- Metabolic syndrome significantly increases the risk of type 2 diabetes and cardiovascular disease (CVD).
- Medically underserved urban communities face disproportionately higher risks and barriers to accessing effective lifestyle interventions.
- Community-based programs are crucial for addressing health disparities in these populations.
Purpose of the Study:
- To evaluate the effectiveness of a community-based modified Diabetes Prevention Program Group Lifestyle Balance (GLB) intervention.
- To assess the intervention's impact on reducing type 2 diabetes and CVD risk in urban individuals with metabolic syndrome.
- To determine the short-term sustainability of clinical outcome improvements.
Main Methods:
- A nonrandomized, prospective, one-group intervention study design was employed.
- Participants (n=88) from 11 urban neighborhoods with metabolic syndrome underwent a 12-week GLB intervention.
- Intervention focused on safe weight loss and physical activity, with 6-month follow-up assessments.
Main Results:
- Significant weight reduction was observed, with 46.4% losing ≥5% body weight and 26.1% losing ≥7%.
- Sustained weight loss was achieved by 87.5% (≥5%) and 66.7% (≥7%) at 6 months.
- Over one-third (43.5%) improved metabolic syndrome components, sustained by 73.3% at 6 months; waist circumference and blood pressure also improved.
Conclusions:
- Community-based GLB interventions are effective in reducing type 2 diabetes and CVD risk for urban adults with metabolic syndrome.
- Short-term sustainability of positive clinical outcomes is feasible.
- Future research should include long-term follow-up to confirm lasting benefits.
Related Concept Videos
01:30Community Based Intervention
Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
01:26Type II Diabetes I: Introduction
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
01:22Diabetes Mellitus: Type 2 and Gestational
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...