Evaluation of human bone around a dental implant retrieved from a subject with osteoporosis

Osteoporosis is a metabolic bone disease that leads to bone fragility and an increase in the risk of bone fracture. Nowadays, osteoporosis may represent a contraindication or a risk factor for osseointegration; however, this field still is controversial in the literature. This article sought to evaluate the bone-to-implant contact of a loaded implant that had been retrieved (due to prosthetic failure) from a woman with Type 1 osteoporosis. Histologically, the implant was osseointegrated and appeared to be surrounded by healthy bone tissue. The bone-to-implant contact demonstrated a mean of 40.07% (+/- 1.07%). No foreign body reaction was found at the bone-to-implant contact, although epithelial downgrowth was observed at the interface. Data from this case report demonstrate that the peri-implant bone histology is not altered even when a patient has been diagnosed with osteoporosis.