Related Experiment Videos
An interleukin-1 receptor antagonist blocks lipopolysaccharide-induced colony-stimulating factor production and early
B E Henricson1, R Neta, S N Vogel
1Department of Microbiology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
Infection and Immunity
|March 1, 1991
Abstract:
In this report, administration of a recombinant interleukin-1 receptor antagonist protein to mice was found to inhibit induction of colony-stimulating factor as well as induction of early endotoxin tolerance by lipopolysaccharide. These findings provide direct evidence that interleukin-1 is an intermediate in these two lipopolysaccharide-induced phenomena.