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'INDOTEST' in atypical hemicrania continua
F Baldacci1, A Nuti, G Cafforio
1Department of Neurosciences, University of Pisa, Pisa, Italy. f.baldacci79@yahoo.it
Insights
Hemicrania continua (HC) is a persistent, one-sided headache. An indomethacin challenge test (INDOTEST) accurately predicted treatment response in patients with atypical HC features, aiding diagnosis and therapy.
Area of Science:
- Neurology
- Headache Medicine
Background:
- Hemicrania continua (HC) is defined as a chronic, strictly unilateral, persistent headache.
- It is known to be responsive to indomethacin treatment.
Observation:
- Three cases of HC with atypical features were analyzed.
- An acute intramuscular indomethacin test (INDOTEST) was administered to these patients.
Findings:
- In all three cases, the INDOTEST successfully predicted a chronic response to indomethacin.
- This suggests the diagnostic utility of INDOTEST in atypical HC presentations.
Implications:
- The INDOTEST may serve as a valuable tool for diagnosing Hemicrania continua, especially in cases with unusual characteristics.
- This diagnostic approach can guide appropriate and timely therapeutic interventions for patients with HC.
Abstract:
Hemicrania continua (HC) is an indomethacin-responsive headache characterized by a chronic, strictly unilateral, side-locked without side-shifting, persistent headache. We report three cases of HC with atypical features in which an acute administration of indomethacin 50 mg IM (INDOTEST) was performed. In all three cases INDOTEST predicted chronic responsiveness to indomethacin. Thus, in cases of HC with atypical features, INDOTEST could help for a correct diagnosis and therapy.
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