Related Experiment Video
Updated: Jul 7, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Seasonality of hypertension
Yassar Y Al-Tamer1, Jasim M T Al-Hayali, Eman A H Al-Ramadhan
1Department of Biochemistry, Ninevah College of Medicine, University of Mosul, Iraq. yassar_altamer@yahoo.co.uk
Insights
Seasonal temperature significantly impacts cardiovascular health. Colder weather is linked to higher blood pressure and serum cholesterol, but lower high-density lipoprotein cholesterol (HDL-C) levels in hypertensive patients.
Area of Science:
- Cardiovascular Physiology
- Environmental Health
- Clinical Medicine
Background:
- Essential hypertension is a prevalent condition with complex influencing factors.
- Environmental variables, such as temperature, may play a role in cardiovascular regulation.
- Understanding these influences is crucial for managing hypertension and cholesterol levels.
Purpose of the Study:
- To investigate the relationship between daily temperature and key cardiovascular risk factors.
- To assess how blood pressure, serum total cholesterol, and HDL-C levels fluctuate with ambient temperature over a year.
- To determine seasonal patterns in these parameters for individuals with essential hypertension.
Main Methods:
- A longitudinal study followed a cohort of controls and patients with essential hypertension for one year.
- Four data collection points were scheduled across different day temperatures.
- Measurements included blood pressure, serum total cholesterol, and high-density lipoprotein cholesterol (HDL-C).
Main Results:
- A significant inverse correlation was observed between mean blood pressure and day temperature.
- Serum total cholesterol levels also showed a significant inverse relationship with day temperature.
- High-density lipoprotein cholesterol (HDL-C) exhibited a significant direct relationship with day temperature.
Conclusions:
- Seasonal variations in temperature influence blood pressure and lipid profiles in patients with essential hypertension.
- Colder seasons are associated with elevated blood pressure and serum total cholesterol.
- Lower high-density lipoprotein cholesterol (HDL-C) levels are observed during colder periods, suggesting a seasonal cardiovascular risk cycle.
Abstract:
In this study, a group of controls and patients with essential hypertension were followed up for 1 year. Four measurements at different day temperatures were performed. In each visit, blood pressure, serum total cholesterol, and high-density lipoprotein cholesterol (HDL-C) were measured. The results showed a significant inverse relationship between mean blood pressure and serum total cholesterol levels with day temperature, while a direct relationship was observed for HDL-C value. These results suggest that in areas where significant changes in day temperature and daylight duration exist at different times of the year, blood pressure, serum cholesterol, and HDL-C levels change accordingly in a cycle with higher blood pressure and serum total cholesterol and lower HDL-C values in the coldest season.
Related Concept Videos
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension I: Introduction
Hypertension and Regulation of Blood Pressure
Hypertension II: Pathophysiology
Factors affecting Blood pressure
Physiological Factors:
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's phenomenon, is a...