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Published on: May 9, 2019
[Effect of Yishen capsule on serum vascular endothelial growth factor and cell immunity in patients with chronic
Xi-li Wu1, Wan-sen Sun, Wang-gang Zhang
1Department of Integrated Chinese Traditional and Western Medicine, Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710004, China. wuxili1984@163.com
Objective:
To explore the effect of Yishen capsule on the serum vascular endothelial growth factor (VEGF), the cell immunity and the theraphic.
Method:
Serum VEGF and T cell subsets were studied in 30 normal subjects and 83 patients before and after treatment.
Result:
Compare with normal subjects, CD3, CD4, CD4/CD8 were decreased, CD8 and serum VEGF were increased obviously (P <0. 05 or P <0. 01). After three months treatment with YiShen capsule, CD4/CD8 was increased, CD8 and serum VEGF were decreased significantly (P <0.05 or P <0.01).
Conclusion:
Yishen capsule can reduce the proteinuria, increase the function of immunity and improve the clinical symptom of patients with chronic glomerulonephritis, achieved the effects of allevating chronic glomerular sclerosis ultimately.