Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hybridization of Atomic Orbitals I03:24

Hybridization of Atomic Orbitals I

The mathematical expression known as the wave function, ψ, contains information about each orbital and the wavelike properties of electrons in an isolated atom. When atoms are bound together in a molecule, the wave functions combine to produce new mathematical descriptions that have different shapes. This process of combining the wave functions for atomic orbitals is called hybridization and is mathematically accomplished by the linear combination of atomic orbitals. The new orbitals that...
Valence Bond Theory and Hybridized Orbitals02:38

Valence Bond Theory and Hybridized Orbitals

According to valence bond theory, a covalent bond results when: (1) an orbital on one atom overlaps an orbital on a second atom, and (2) the single electrons in each orbital combine to form an electron pair. The strength of a covalent bond depends on the extent of overlap of the orbitals involved. Maximum overlap is possible when the orbitals overlap on a direct line between the two nuclei.
A σ bond (single bond in a Lewis structure) is a covalent bond in which the electron density is...
Molecular Orbital Theory II03:51

Molecular Orbital Theory II

Molecular Orbital Energy Diagrams
Chemical Bonds02:40

Chemical Bonds


Atoms participate in a chemical bond formation to acquire a completed valence-shell electron configuration similar to that of the noble gas nearest to it in atomic number. Ionic, covalent, and metallic bonds are some of the important types of chemical bonds. Bond energy and bond length determine the strength of a chemical bond.
Types of Chemical Bonds
An ionic bond is formed due to electrostatic attraction between cations and anions. Often, the ions are formed by the transfer of electrons from...
Hybridization of Atomic Orbitals II03:35

Hybridization of Atomic Orbitals II

sp3d and sp3d 2 Hybridization
Valence Bond Theory02:45

Valence Bond Theory

Overview of Valence Bond Theory

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unexpected bonding ambiguity of the open/closed-shell R<sub>2</sub>PO ligand family: the case of phosphinoyl <i>vs.</i> phosphoryl if bound to transition metals in their low oxidation state.

Dalton transactions (Cambridge, England : 2003)·2025
Same author

Activation of Electrophilic Reactivity by Protonation and Oxidation of a Peroxo Co<sup>III</sup>Co<sup>III</sup> Complex: Reactivity and Molecular Structures of Hydroperoxo, Superoxo, and Peroxo Co<sup>III</sup>Co<sup>III</sup> Complexes.

Journal of the American Chemical Society·2025
Same author

Probing Magnetic Excitations in Co<sup>II</sup> Single-Molecule Magnets by Inelastic Neutron Scattering.

European journal of inorganic chemistry·2024
Same author

Trapping of a phenoxyl radical at a non-haem high-spin iron(II) centre.

Nature chemistry·2024
Same author

Reactive high-spin iron(IV)-oxo sites through dioxygen activation in a metal-organic framework.

Science (New York, N.Y.)·2023
Same author

Synthesis, Structure and Reactivity of a Mononuclear N,N,O-Bound Fe(II) α-Keto-Acid Complex.

Chemistry (Weinheim an der Bergstrasse, Germany)·2023

Related Experiment Video

Updated: Jul 7, 2026

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy
10:37

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy

Published on: March 16, 2020

Secondary bonding interactions in biomimetic [2Fe-2S] clusters.

Joachim Ballmann1, Sebastian Dechert, Eckhard Bill

  • 1Institut für Anorganische Chemie, Georg-August-Universität, Tammannstrasse 4, D-37077 Göttingen, Germany.

Inorganic Chemistry
|February 9, 2008
PubMed
Summary

Synthetic [2Fe-2S] complexes with ether and thioether donors were created to model biological iron-sulfur clusters. These models reveal secondary bonding interactions, offering insights into cluster function.

More Related Videos

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

Facet-to-facet Linking of Shape-anisotropic Colloidal Cadmium Chalcogenide Nanostructures
09:12

Facet-to-facet Linking of Shape-anisotropic Colloidal Cadmium Chalcogenide Nanostructures

Published on: August 10, 2017

Related Experiment Videos

Last Updated: Jul 7, 2026

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy
10:37

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy

Published on: March 16, 2020

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

Facet-to-facet Linking of Shape-anisotropic Colloidal Cadmium Chalcogenide Nanostructures
09:12

Facet-to-facet Linking of Shape-anisotropic Colloidal Cadmium Chalcogenide Nanostructures

Published on: August 10, 2017

Area of Science:

  • Bioinorganic Chemistry
  • Organometallic Chemistry
  • Coordination Chemistry

Background:

  • Biological [2Fe-2S] clusters are vital metalloenzymes.
  • Understanding their active sites is crucial for deciphering biochemical pathways.
  • Synthetic models aid in elucidating the structural and electronic properties of these clusters.

Purpose of the Study:

  • To synthesize novel synthetic [2Fe-2S] complexes.
  • To investigate the role of tethered ether and thioether moieties.
  • To model potential interactions in biological [2Fe-2S] clusters.

Main Methods:

  • Synthesis of six new [2Fe-2S] complexes.
  • X-ray crystallography for structural determination.
  • Density functional theory (DFT) calculations.
  • Spectroscopic analyses (UV-vis, Mössbauer, 1H NMR).
  • Magnetic susceptibility (SQUID) and cyclic voltammetry.

Main Results:

  • Structures of six [2Fe-2S] complexes with varying ligands were determined.
  • Secondary bonding interactions involving ether-O and thioether-S were confirmed.
  • DFT calculations showed significant spin density on these fifth donor atoms.
  • Spectroscopic and electrochemical data provided insights into electronic properties.

Conclusions:

  • The synthetic models successfully mimic aspects of biological [2Fe-2S] clusters.
  • Secondary bonding interactions play a role in the electronic structure.
  • These findings contribute to understanding the function of iron-sulfur proteins.