Invasive bacterial diseases in northern Canada
Related Experiment Video
Updated: Jul 7, 2026

Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae
Published on: January 17, 2014
Naushaba Degani1, Christine Navarro, Shelley L Deeks
1Child Health Evaluative Services Unit, Hospital for Sick Children, Toronto, Ontario, Canada.
Abstract:
International Circumpolar Surveillance (ICS) is a population-based invasive bacterial disease surveillance network. Participating Canadian regions include Yukon, Northwest Territories, Nunavut, and northern regions of Québec and Labrador (total population 132,956, 59% aboriginal). Clinical and demographic information were collected by using standardized surveillance forms. Bacterial isolates were forwarded to reference laboratories for confirmation and serotyping. After pneumococcal conjugate vaccine introduction, crude annual incidence rates of invasive Streptococcus pneumoniae decreased from 34.0/100,000 population (1999-2002) to 23.6/100,000 population (2003-2005); substantial reductions were shown among aboriginals. However, incidence rates of S. pneumoniae, Haemophilus influenzae, and group A streptococci were higher in aboriginal populations than in non-aboriginal populations. H. influenzae type b was rare; 52% of all H. influenzae cases were caused by type a. Data collected by ICS contribute to the understanding of the epidemiology of invasive bacterial diseases among northern populations, which assists in formulation of prevention and control strategies, including immunization recommendations.
Related Concept Videos
Bacterial Meningitis
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Clinical Significance of Antibiotic Resistance
Bacterial Signaling
Colonisation of Pathogens
