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Intraductal Delivery to the Rabbit Mammary Gland
06:30

Intraductal Delivery to the Rabbit Mammary Gland

Published on: March 9, 2017

Locally advanced and inflammatory breast cancer

Stephen Chia1, Sandra M Swain, David R Byrd

  • 1Department of Medical Oncology, British Columbia Cancer Agency, 600 West 10th Ave, Vancouver, British Columbia, Canada. schia@bccancer.bc.ca

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
|February 9, 2008
PubMed
Abstract

No abstract available in PubMed .

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Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

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