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Gender difference in blood pressure control and cardiovascular risk factors in Americans with diagnosed hypertension
Kwok Leung Ong1, Annette W K Tso, Karen S L Lam
1Department of Medicine, University of Hong Kong, Hong Kong.
Insights
Blood pressure control is similar in men and women with hypertension. However, women have more other cardiovascular risk factors, highlighting the need for comprehensive management.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Hypertension is a major risk factor for cardiovascular disease (CVD), the leading cause of death in women.
- Understanding gender-specific trends in hypertension management and associated risk factors is crucial for public health initiatives.
Purpose of the Study:
- To analyze gender-specific trends in blood pressure control among US adults with diagnosed hypertension.
- To assess the prevalence of five other cardiovascular risk factors in relation to gender and hypertension status.
Main Methods:
- Analysis of data from 3475 US adults (aged >=18) with diagnosed hypertension from the National Health and Nutrition Examination Survey (1999-2004).
- Evaluation of age-adjusted prevalence of uncontrolled blood pressure and five other risk factors: central obesity, elevated total cholesterol, low high-density lipoprotein cholesterol, hyperglycemia, and smoking.
- Comparison of gender-specific trends and prevalence rates over the study period.
Main Results:
- Uncontrolled blood pressure prevalence was similar between men (50.8%) and women (55.9%) and did not change significantly over time.
- Women exhibited significantly higher prevalence of central obesity (79.0%), elevated total cholesterol (61.3%), and low high-density lipoprotein cholesterol (39.7%) compared to men.
- The proportion of individuals with >=3 risk factors was higher in women (52.5%) than men (40.9%), decreasing significantly in women from 1999-2000 to 2003-2004.
Conclusions:
- Blood pressure control in women with hypertension is comparable to men and showed no significant time-related changes from 1999-2004.
- Women with hypertension present a higher burden of concomitant cardiovascular risk factors, necessitating targeted interventions.
- Improving blood pressure control and addressing co-existing risk factors in women with hypertension are critical for CVD prevention.
Abstract:
Hypertension is an important risk factor for cardiovascular disease, which is the leading cause of death in women. We, therefore, analyzed gender-specific trends in the control of blood pressure and prevalence of 5 other cardiovascular risk factors (central obesity, elevated total cholesterol, low high-density lipoprotein cholesterol, hyperglycemia, and smoking) among adults with diagnosed hypertension in the United States. We included 3475 participants aged >or=18 years with diagnosed hypertension in the National Health and Nutrition Examination Survey 1999-2004. The age-adjusted prevalence of uncontrolled blood pressure was 50.8+/-2.1% in men and 55.9+/-1.5% in women, which were not significantly different and had not changed significantly with time. Central obesity, elevated total cholesterol level, and low high-density lipoprotein cholesterol were significantly more prevalent in women than in men (79.0+/-1.0%, 61.3+/-1.6%, and 39.7+/-1.6% versus 63.9+/-1.6%, 48.1+/-1.8%, and 35.6+/-1.7%, respectively; P<0.05). The age-adjusted proportion with >or=3 of the 6 risk factors studied was higher in women than in men (52.5+/-1.4% versus 40.9+/-1.8%; P<0.001), and this proportion decreased significantly by 7.7% in women from 1999-2000 to 2003-2004 (P<0.05) but not in men. Our study shows that blood pressure control in women with diagnosed hypertension was not significantly inferior compared with men and had not changed significantly in 1999-2004. However, women had higher prevalence of other concomitant cardiovascular risk factors. Although there is room for improvement in blood pressure control, our study has highlighted the importance of addressing concomitant cardiovascular risk factors in women with hypertension.
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