Related Experiment Video
Updated: Jul 7, 2026
Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
Published on: September 17, 2014
[Descemet's stripping with automated endothelial keratoplasty (DSAEK)]
1Augenklinik mit Poliklinik, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen, Germany. ccursiefen@yahoo.com
Background:
Although penetrating keratoplasty remains the gold standard for surgically treating corneal endothelial pathologies, tremendous progress has been made in recent years to improve the technology of (posterior) lamellar keratoplasty.
Methods:
Literature review from PubMed and own data.
Results:
Posterior lamellar keratoplasty using a microkeratome (Descemet's stripping with automated endothelial keratoplasty, or DSAEK) is a reliable surgical technique for Fuchs' endothelial dystrophy and pseudophakic bullous keratopathy. Visual rehabilitation is faster with lamellar keratoplasty than penetrating keratoplasty.
Conclusion:
Posterior lamellar keratoplasty techniques such as DSAEK will become an important surgical treatment option for corneal endothelial pathologies.
