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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Factors Affecting Erythropoiesis01:24

Factors Affecting Erythropoiesis

The cardiovascular system regulates the number of erythrocytes in the bloodstream to ensure optimal oxygen transport. It also prevents over-proliferation of these cells, which helps to maintain blood viscosity and flow rate.
Several factors influence the erythrocyte production rate, with tissue oxygen level being among the most critical. Intense exercise or high altitudes can cause tissue hypoxia, which triggers the kidneys to release more erythropoietin (EPO) into the bloodstream.
EPO then...

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Articles linked to this work by shared authors, journal, and citation graph.

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The humanitarian aspects of organ transplantation.

Transplant international : official journal of the European Society for Organ Transplantation·2001
Same author

Successful ex vivo liver perfusion system for hepatic failure pending liver regeneration or liver transplantation.

Transplantation proceedings·2001
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Extracorporeal liver perfusion system for successful hepatic support pending liver regeneration or liver transplantation: a pre-clinical controlled trial.

Transplantation·1999
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Mycophenolate mofetil immunosuppression in high-risk renal transplant recipients.

Transplantation proceedings·1998
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Long-term function and survival of elderly donor kidneys transplanted into young adults.

Transplantation·1998
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Experience with transplantation of elderly donor kidneys.

Transplantation proceedings·1998

Related Experiment Video

Updated: Jul 7, 2026

Study of Experimental Organ Donation Models for Lung Transplantation
08:56

Study of Experimental Organ Donation Models for Lung Transplantation

Published on: March 15, 2024

Organ shortage crisis: problems and possible solutions.

G M Abouna1

  • 1Drexel University, College of Medicine, Philadelphia, Pennsylvania, USA. gmabouna@comcast.net

Transplantation Proceedings
|February 12, 2008
PubMed
Summary

The global organ shortage crisis, driven by rising organ failure and transplant success, leads to long waiting lists and deaths. Implementing strategies like public education and incentivized donation can save lives.

Area of Science:

  • Transplantation Medicine
  • Public Health Policy

Background:

  • Global demand for organ transplantation is increasing due to rising organ failure rates and improved transplant outcomes.
  • A critical shortage of available organs for transplantation exists, leading to longer waiting lists and increased patient mortality.
  • This shortage impacts patient quality of life and escalates healthcare costs for alternative treatments like dialysis.

Purpose of the Study:

  • To address the critical organ shortage crisis in transplantation.
  • To explore and propose practical solutions to increase organ availability for patients in need.

Main Methods:

  • Reviewing and proposing various strategies to enhance organ procurement.
  • Discussing the implementation of educational programs for the public and healthcare professionals.

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Exploring Alternative Perfusion Solutions Using Next-Generation Polymerized Hemoglobin-Based Oxygen Carriers in a Model of Rat Ex Vivo Lung Perfusion
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Exploring Alternative Perfusion Solutions Using Next-Generation Polymerized Hemoglobin-Based Oxygen Carriers in a Model of Rat Ex Vivo Lung Perfusion

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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

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Related Experiment Videos

Last Updated: Jul 7, 2026

Study of Experimental Organ Donation Models for Lung Transplantation
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Study of Experimental Organ Donation Models for Lung Transplantation

Published on: March 15, 2024

Exploring Alternative Perfusion Solutions Using Next-Generation Polymerized Hemoglobin-Based Oxygen Carriers in a Model of Rat Ex Vivo Lung Perfusion
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Exploring Alternative Perfusion Solutions Using Next-Generation Polymerized Hemoglobin-Based Oxygen Carriers in a Model of Rat Ex Vivo Lung Perfusion

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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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  • Evaluating the potential of utilizing extended criteria donors and paired organ donation.
  • Examining concepts such as presumed consent, rewarded gifting, altruistic donation, and controlled financial incentives for donors.

    • Main Results:

    • The study outlines several pathways to effectively address the organ shortage.
    • Proposed strategies include public and professional education, utilization of marginal donors, paired donation, presumed consent, and various forms of incentivized or altruistic donation.
    • Successful implementation of these strategies, with ethical considerations, can eliminate the organ shortage crisis.

    Conclusions:

    • The organ shortage crisis is a significant global health challenge.
    • A multi-faceted approach involving policy changes, public engagement, and innovative donation models is necessary.
    • Implementing proposed strategies can substantially increase organ availability, save lives, and improve patient outcomes through transplantation.