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Coronary artery calcifications in hemodialysis patients and their correlation with the prevalence of erectile
1Department of Urology, Hacettepe University, School of Medicine, Shihiye, Ankara, Turkey. kuinci@hacettepe.tr
Insights
Erectile dysfunction (ED) is highly prevalent in hemodialysis patients, with 82.9% experiencing some form of ED. Severe ED correlates with higher coronary artery calcium scores (CACS).
Area of Science:
- Nephrology
- Cardiology
- Urology
Background:
- Hemodialysis patients frequently experience comorbidities.
- Erectile dysfunction (ED) is a common concern in this population.
- Coronary artery calcium scores (CACS) indicate cardiovascular calcification.
Purpose of the Study:
- To determine the prevalence of ED in hemodialysis patients.
- To investigate the correlation between ED severity and CACS.
Main Methods:
- Thirty-five male hemodialysis patients were assessed.
- Coronary artery calcium scores (CACS) were measured using computed tomography.
- Erectile function was evaluated using the International Index of Erectile Function (IIEF) questionnaire.
Main Results:
- The prevalence of any ED was 82.9%, with 40% experiencing severe ED.
- Patients with severe ED had significantly higher CACS (P = .032).
- A moderate negative correlation was found between IIEF-5 scores and CACS (r = -.420, P = .012).
Conclusions:
- Erectile dysfunction (ED) is highly prevalent among hemodialysis patients.
- Increased CACS is associated with greater ED severity in this cohort.
- While multiple factors may contribute to ED, CACS is a significant correlate.
Introduction:
Our aim in this study was to investigate the prevalence and correlation with coronary artery calcium scores (CACS) and erectile dysfunction (ED) among hemodialysis patients.
Patients And Methods:
Thirty-five male patients with chronic renal failure were selected to participate in this study. All patients underwent examinations for CACS using 16-channel multidetector computed tomography. The presence and severity of ED were determined by calculating the erectile function domain of the self-administered International Index of Erectile Function (IIEF).
Results:
The patients' ages ranged from 22 to 78 with a mean of 51.6 years. The mean duration of hemodialysis was 75.7 months (range = 12 to 232). Twenty-six patients had a history of one or more systemic diseases. The prevalence of any level of ED was 82.9% for all hemodialysis patients, and severe ED, 40%. The CACS was significantly higher among patients with severe ED (P = .032). The IIEF-5 score was also shown to have a moderate negative correlation with the CACS (r = -.420, P = .012). Age, duration of hemodialysis, body mass index, diabetes mellitus, hypertension, coronary heart diseases, hyperlipidemia, thyroid disease, depression, tobacco consumption, and medication were not associated with the presence of ED (P > .05).
Conclusion:
ED is prevalent in hemodialysis patients. Although many possible factors contribute to ED, the severity of ED increases with greater CACS.
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