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Updated: Jul 7, 2026

Measuring Delay Discounting in Humans Using an Adjusting Amount Task
Published on: January 9, 2016
Delay may reduce procedural risk, but at what price to the patient?
1Department of Vascular Surgery at Leicester Royal Infirmary, Leicester, UK. ross.naylor@uhl-tr.nhs.uk
Insights
Expedited carotid endarterectomy (CEA) within 1-2 weeks of TIA or minor stroke is recommended due to high early risk. This strategy can be reconciled with surgical concerns regarding perioperative outcomes.
Area of Science:
- Vascular Surgery
- Neurology
- Public Health
Background:
- The highest risk for stroke recurrence or major vascular events occurs within the first seven days after a transient ischemic attack (TIA) or minor stroke.
- Current stroke/vascular services often face resource limitations, hindering the timely implementation of expedited interventions.
- A significant focus exists on treating asymptomatic individuals, potentially diverting resources from high-risk symptomatic patients.
Purpose of the Study:
- To review the evidence supporting the expedited surgical intervention strategy for TIA and minor stroke.
- To address and reassure surgeons about potential concerns regarding perioperative outcomes associated with early carotid endarterectomy (CEA) in symptomatic patients.
Main Methods:
- Literature review of evidence supporting expedited intervention for TIA and minor stroke.
- Analysis of data and studies related to perioperative outcomes of early CEA in symptomatic patients.
Main Results:
- Evidence strongly supports performing CEA within 1-2 weeks of a TIA or minor stroke due to the critical early risk period.
- The paper aims to demonstrate that expedited CEA in symptomatic patients can achieve acceptable perioperative outcomes, despite initial concerns.
Conclusions:
- A strategy of expedited CEA for TIA and minor stroke is evidence-based and crucial for patient safety.
- Surgeons can be reassured that early intervention is feasible and can be reconciled with managing perioperative risks effectively.
Abstract:
The renewed strategy towards performing carotid endarterectomy (CEA) within 1-2 weeks of a patient presenting with a TIA or minor stroke is based on a large body of evidence showing that the highest risk period for the patient is the first seven days after the index event. Unfortunately, most stroke/vascular services are inadequately resourced to achieve this target and many are more likely to be pre-occupied with treating large numbers of asymptomatic individuals. This paper reviews the evidence underlying the current drive towards expedited intervention in patients presenting with TIA and minor stroke. It will also try to provide reassurance to the surgeon as to how such a strategy can be reconciled with understandable concerns that early CEA in symptomatic patients is associated with poorer perioperative outcomes.
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