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Infantile cortical hyperostosis of the mandible

Yiu-kai Wong1, Jason Chi-fung Cheng

  • 1Oral-Maxillofacial Surgery and Dental Unit, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong. wykj@graduate.hku.hk

The British Journal of Oral & Maxillofacial Surgery
|February 12, 2008
PubMed

Insights

Infantile cortical hypersotosis, a rare bone disorder, can affect infants within the first six months. This case highlights successful indometacin treatment for mandibular involvement in a 3-month-old.

Area of Science:

  • Pediatric medicine
  • Skeletal biology
  • Rare disease research

Background:

  • Infantile cortical hypersotosis (ICH) is a rare genetic disorder.
  • Characterized by excessive periosteal bone formation in infants.
  • Typically presents within the first six months of life.

Observation:

  • A 3-month-old male infant presented with symptoms of ICH.
  • The condition specifically affected the left mandible.
  • The patient was treated with indometacin.

Findings:

  • The case demonstrates the occurrence of ICH in the mandible.
  • Indometacin was utilized as a therapeutic intervention.
  • Clinical outcomes of indometacin treatment in this specific ICH presentation are detailed.

Implications:

  • This report expands the understanding of ICH manifestations.
  • It suggests indometacin as a potential treatment option for mandibular ICH.
  • Further research into non-syndromic ICH and its management is warranted.

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