Ultrasonic phased arrays with variable geometric focusing for hyperthermia applications

Area of Science:

• Biomedical Engineering
• Medical Physics
• Acoustic Technology

Background:

• Deep-localized hyperthermia requires precise temperature control for effective cancer treatment.
• Existing ultrasonic applicators often lack dynamic focusing capabilities in all dimensions.

Purpose of the Study:

• To investigate a novel ultrasonic applicator for deep-localized hyperthermia.
• To develop an applicator with combined electronic and variable geometric focusing.
• To assess the impact of a dynamic liquid lens on focusing capabilities.

Main Methods:

• Development of a linear phased array for electronic focusing.
• Integration of a spherical liquid lens for variable geometric focusing.
• Comparison of computer simulations with experimental measurements of field intensity.
• Analysis of design parameters including liquid choice and array element configuration.

Main Results:

• The prototype applicator demonstrated combined electronic and geometric focusing.
• Dynamic control of the liquid lens allowed for adjustable geometric focus.
• Simulations and experimental data showed good agreement for field intensity distribution.
• Key design parameters influencing performance were identified.

Conclusions:

• The investigated ultrasonic applicator offers enhanced precision for deep-localized hyperthermia.
• The integration of a dynamic liquid lens provides crucial focusing control.
• This technology holds promise for improved thermal therapy delivery.