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Updated: Jul 7, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Longitudinal quality of life in low-income men in a state-funded prostate cancer treatment program
Mary Wassel Zavala1, Sally L Maliski, Lorna Kwan
1Department of Urology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095-1738, USA.
Objectives:
To evaluate longitudinal changes in disease-specific health-related quality of life (HRQOL) among a cohort of low-income men treated for prostate cancer.
Methods:
Three hundred fifty-seven participants in a state-funded program that provides free prostate cancer treatment to uninsured, low-income men completed written surveys and telephone interviews containing validated measures of general and disease-specific HRQOL. Assessments were made at study enrollment and at subsequent times. Determinants of change were identified with repeated-measures analyses.
Results:
We found a significant interaction between the acute surgical treatment effects and time of assessment. Men exposed longer to the program's supportive and educational interventions reported less severe declines in post-operative urinary and bowel HRQOL than others.
Conclusions:
Demographic covariates predicted general and disease-specific domains of HRQOL. Among patients treated with surgery, longer duration of pre-treatment program enrollment was associated with better outcomes.
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