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In vitro selection of RNA aptamers to a protein target by filter immobilization

S D Jhaveri1, A D Ellington

  • 1University of Texas, Austin, Texas, USA.

Current Protocols in Molecular Biology
|February 12, 2008
PubMed

Abstract:

In vitro selection of RNA aptamers that bind to a protein target is detailed in the protocols presented in this unit. Aptamers generated from these types of selection experiments can potentially function as protein inhibitors, and are often used as diagnostic or therapeutic reagents.

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