Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Blood Studies for Cardiovascular System III: Serum Lipid Profile

Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Temperature determines early-life success of burbot Lota lota eggs.

Journal of fish biology·2026

Same author

Western diet-induced MASH in PWK/PhJ mice identifies disruptions in amino acid and sphingolipid metabolism contributing to cardiac dysfunction.

Nature communications·2026

Same author

Endometrial NCOR1 deficiency contributes to implantation failure in endometriosis-associated infertility.

iScience·2026

Same author

The PM20D1-OLE pathway induces microglia rewiring to ameliorate Alzheimer disease.

Cell death & disease·2026

Same author

Dynamics of genetic and somatic trade-offs in ageing and mortality.

Nature·2026

Same author

How to train your rodent: Recommendations for the preclinical study of exercise-induced benefits in metabolic research.

Cell metabolism·2026

Search research articles

Related Experiment Video

Updated: Jul 7, 2026

Determination of Total Lipid and Lipid Classes in Marine Samples

Determination of Total Lipid and Lipid Classes in Marine Samples

Published on: December 11, 2021

Lipid and bile acid analysis.

Carmen A Argmann¹, Sander M Houten, Marie-France Champy

¹Institut de Genetique et de Biologie Moleculaire et Cellulaire, Illkirch, France.

Current Protocols in Molecular Biology

|February 12, 2008

Summary

This study details methods for analyzing lipid metabolism in mouse models, crucial for understanding diseases like obesity and atherosclerosis. It highlights key differences in lipid homeostasis between mice and humans, essential for accurate data interpretation.

More Related Videos

Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids

Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids

Published on: May 15, 2019

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis

Published on: November 17, 2011

Related Experiment Videos

Last Updated: Jul 7, 2026

Determination of Total Lipid and Lipid Classes in Marine Samples

Determination of Total Lipid and Lipid Classes in Marine Samples

Published on: December 11, 2021

Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids

Isolation of Lipoprotein Particles from Chicken Egg Yolk for the Study of Bacterial Pathogen Fatty Acid Incorporation into Membrane Phospholipids

Published on: May 15, 2019

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis

Published on: November 17, 2011

Area of Science:

Biochemistry and Molecular Biology
Metabolic Research
Animal Models in Disease Research

Background:

Lipids are essential for cellular function, energy storage, and signaling, playing a vital role in maintaining homeostasis.
Dysregulation of lipid homeostasis is implicated in numerous diseases, including atherosclerosis, inflammatory disorders, and obesity.
Mouse models are frequently utilized to study lipid metabolism and its associated pathologies.

Purpose of the Study:

To describe established methods for analyzing lipid metabolism in mouse models, covering both blood and tissue analyses.
To discuss the similarities and critical differences in lipid homeostasis between mice and humans.
To provide guidance for the accurate extrapolation of lipid data from mouse studies to human physiology.

Main Methods:

Detailed description of commonly employed techniques for evaluating lipid profiles in mouse blood.
Explanation of methods for assessing lipid content and distribution within various mouse tissues.
Comparative analysis of lipid metabolism pathways in murine and human systems.

Main Results:

Comprehensive overview of validated techniques for mouse lipid metabolism analysis.
Identification of key metabolic pathways and lipid parameters measurable in mice.
Highlighting of species-specific variations in lipid handling and homeostasis.

Conclusions:

Standardized methods enable robust analysis of mouse lipid metabolism.
Understanding interspecies differences is critical for translating mouse study findings to human health.
Accurate interpretation of mouse lipid data is essential for advancing research into metabolic diseases.