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Published on: July 17, 2020

Isoxazoles from 1,1-Disubstituted Bromoalkenes

Sureshbabu Dadiboyena1, Jianping Xu, Ashton T Hamme

  • 1Department of Chemistry, Jackson State University, Jackson, Mississippi 39217, USA.

Tetrahedron Letters
|February 13, 2008
PubMed
Summary

This study presents a regioselective synthesis for 3,5-disubstituted isoxazoles. The method utilizes 1,3-dipolar cycloaddition with 1,1-disubstituted bromoalkenes, forming key intermediates that readily aromatize.

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