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Metabolic control in type 2 diabetes correlates weakly with patient adherence to oral hypoglycaemic treatment
Seng Cheong Loke1, Michelle Jong
1Department of Medicine, Faculty of Medicine and Health Science Universiti Putra Malaysia, Malaysia. lokesengcheong@yahoo.com.sg
Introduction:
Patient adherence to treatment is viewed as essential to good metabolic control in diabetes. Our primary objective was to determine if self-reported patient adherence correlated strongly with metabolic control. Our secondary objective was to determine the natural grouping of factors which influence adherence.
Materials And Methods:
Data were collected using a questionnaire set with 5-point Likert scales. Primary analysis was done using Spearman's correlation coefficient between self-reported composite adherence scores and HbA1c. Secondary analysis was done using exploratory factor analysis.
Results:
The primary analysis suggests that patient adherence to the treatment regime is weakly correlated to metabolic control. Calculated Spearman's rho was 0.197, with a two-tailed P value of 0.027. The secondary analysis demonstrates the natural clustering of factors that influence patient adherence to treatment. A 6-factor solution was found to account for most of the variance in the data. We also found that feelings of frustration, anxiety, and depression were associated with a lack of knowledge about diabetes treatment. In addition, belief in traditional medicine correlated strongly with ethnicity.
Conclusion:
A good treatment regime for type 2 diabetes mellitus influences metabolic outcome far more than patient adherence.
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