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Related Concept Videos

Bioreactor Design and Operational System01:29

Bioreactor Design and Operational System

Bioreactors are engineered vessels designed to cultivate microorganisms under controlled conditions for industrial bioprocessing. They maintain sterility and allow precise regulation of pH, temperature, oxygen, and nutrient levels to optimize microbial growth and metabolite production. Bioreactors range from small laboratory units of 1 liter to industrial systems holding up to 500,000 liters, though only about 75% of their volume is actively used for fermentation. The remaining headspace...
Designing Growth Media for Bioreactors01:30

Designing Growth Media for Bioreactors

Growth media provide essential nutrients that support cell growth and metabolism, thereby enhancing the yield of valuable products such as enzymes, antibiotics, and biomass. Designing an effective growth medium involves balancing all components to prevent nutrient limitations or toxic excesses, both of which can impair growth and reduce product yields.Composition of a Typical Growth MediumA typical growth medium contains carbon and nitrogen sources, salts, vitamins, trace elements, and...
Bioreactor Controls-II01:18

Bioreactor Controls-II

In aerobic fermentations, oxygen is vital for microbial growth and metabolite production. Since air comprises only about 20% oxygen and the gas is poorly soluble in water—just 9 ppm at 20°C—supplying sufficient oxygen becomes a critical challenge, especially in high-demand processes like yeast growth or citric acid production. Even a fully saturated broth may offer only a few seconds of oxygen availability.To address this, sterile or scrubbed air is introduced into the fermentor via a sparger...
Upstream Processing01:27

Upstream Processing

Upstream processing represents a critical phase in biomanufacturing, wherein biological systems such as microorganisms, mammalian cells, or insect cells are cultivated to produce therapeutic proteins, vaccines, enzymes, or other biologically derived products. This phase encompasses all steps from the selection and genetic manipulation of the production organism to the cultivation of cells in bioreactors under tightly controlled environmental conditions.Host Selection and Genetic OptimizationThe...
Bioreactor Controls-I01:28

Bioreactor Controls-I

Maintaining optimal conditions within fermenters is essential for maximizing microbial productivity and ensuring process efficiency. This lesson focuses on key parameters—temperature, foam, pH, carbon dioxide, oxygen, and pressure—and their precise measurement and control strategies in fermentation systems.Temperature ControlTemperature regulation is critical due to the exothermic nature of many fermentation processes. In small laboratory fermenters, temperature is commonly monitored using...
Bioreactor Controls-III01:22

Bioreactor Controls-III

Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...

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Related Experiment Video

Updated: Jul 7, 2026

Operation of Laboratory Photobioreactors with Online Growth Measurements and Customizable Light Regimes
05:21

Operation of Laboratory Photobioreactors with Online Growth Measurements and Customizable Light Regimes

Published on: October 28, 2021

Design process of an area-efficient photobioreactor.

Jan-Willem F Zijffers1, Marcel Janssen, Johannes Tramper

  • 1Food and Bioprocess Engineering Group, Wageningen University, 6700 EV, Wageningen, the Netherlands. jan-willem.zijffers@wur.nl

Marine Biotechnology (New York, N.Y.)
|February 13, 2008
PubMed
Summary

The Green Solar Collector (GSC) is an area-efficient photobioreactor designed for microalgae cultivation. It efficiently delivers sunlight to algae for optimal biomass production, maximizing productivity per area.

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Microalgae Cultivation and Biomass Quantification in a Bench-Scale Photobioreactor with Corrosive Flue Gases
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Construction and Setup of a Bench-scale Algal Photosynthetic Bioreactor with Temperature, Light, and pH Monitoring for Kinetic Growth Tests
10:08

Construction and Setup of a Bench-scale Algal Photosynthetic Bioreactor with Temperature, Light, and pH Monitoring for Kinetic Growth Tests

Published on: June 14, 2017

Area of Science:

  • Biotechnology
  • Renewable Energy Engineering
  • Algal Cultivation

Background:

  • Efficient microalgae cultivation is crucial for sustainable biomass production.
  • Existing photobioreactors often face limitations in light delivery and area efficiency.
  • Optimizing light utilization is key to maximizing algal biomass yield.

Purpose of the Study:

  • To design an area-efficient photobioreactor, the Green Solar Collector (GSC), for outdoor microalgae cultivation.
  • To ensure efficient delivery and utilization of incident sunlight for algal biomass formation.
  • To develop a system that maximizes biomass productivity per unit area.

Main Methods:

  • Formulated design goals and specified constraints for the GSC.
  • Generated prototype specifications focusing on form and function.
  • Integrated light capturing, transportation, and distribution mechanisms.
  • Utilized vertical plastic light guides and linear Fresnel lenses for sunlight focusing and delivery.

Main Results:

  • Designed a GSC system that captures and delivers sunlight efficiently to microalgae.
  • Incorporated internal reflection and scattering within light guides for uniform light distribution.
  • Optimized light intensity entering the photobioreactor compartments for efficient biomass utilization.
  • Achieved high biomass productivities per area through integrated light management.

Conclusions:

  • The Green Solar Collector design effectively addresses area efficiency in microalgae cultivation.
  • The GSC system demonstrates a novel approach to optimizing light delivery and utilization.
  • The design facilitates high biomass yields, making it promising for large-scale applications.