Prediabetes: a must to recognise disease state

W Shehab Eldin1, M Emara, A Shoker

  • 1Department of Medicine, University of Saskatchewan, Royal University Hospital, Saskatoon, Canada.

Insights

Prediabetes mellitus (PDM) is a curable disease, not just a precursor to type 2 diabetes. Early diagnosis and adherence to treatment guidelines are crucial for managing this condition.

Area of Science:

  • Endocrinology
  • Metabolic Disorders

Background:

  • Prediabetes mellitus (PDM) signifies abnormal glucose homeostasis, characterized by insulin deficiency or resistance.
  • PDM precedes overt type 2 diabetes and is linked to increased mortality and morbidity, meeting disease criteria.

Purpose of the Study:

  • To elevate awareness of PDM as a distinct disease state requiring early intervention.
  • To advocate for PDM to be recognized as a disease rather than a 'pre' stage of diabetes.

Main Methods:

  • Reviewing diagnostic guidelines for PDM.
  • Discussing the prevalence and associated hazards of PDM.
  • Elaborating on current PDM treatment guidelines.

Main Results:

  • Sufficient evidence confirms that PDM is a curable disease state.
  • Current treatment protocols for PDM are effective.

Conclusions:

  • Adherence to established PDM treatment recommendations is essential.
  • Exploration of additional pharmacological agents for PDM management is warranted.
Abstract

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