Related Experiment Video
Updated: Jul 7, 2026

12:24
Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
Published on: July 17, 2012
Ultrasound imaging through time-domain diffraction tomography
1Drexel Univ., Philadelphia, PA.
Summary
Time-domain diffraction tomography precisely maps medium density using acoustic scatter data. Limited pulse bandwidth, however, restricts reconstruction accuracy by filtering spatial frequencies.
Area of Science:
- Physics
- Acoustics
- Imaging Science
Background:
- Time-domain diffraction tomography (TDCT) is an imaging technique.
- It maps medium parameters like density using acoustic scatter data from a single pulse.
- The Born approximation is often used for inversion.
Purpose of the Study:
- To discuss the principles and performance of TDCT.
- To investigate the impact of limited pulse bandwidth on reconstruction accuracy.
- To characterize the limitations of TDCT.
Main Methods:
- Utilized computer simulations of TDCT equations.
- Applied the Born approximation for inversion.
- Investigated parameter variations and pulse bandwidth effects through numerical experiments.
Main Results:
- Under ideal conditions and valid Born approximation, TDCT can accurately reconstruct parameter variations.
- Limited pulse bandwidth degrades reconstruction quality.
- Reconstruction limitations are attributed to a spatial filtering effect eliminating spatial frequencies.
Conclusions:
- TDCT offers precise imaging when Born approximations are valid and sufficient bandwidth is available.
- Pulse bandwidth is a critical factor influencing the accuracy of TDCT reconstructions.
- Understanding these limitations is key for effective application of TDCT.
Related Concept Videos
Ultrasonography
Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...
During an ultrasonography procedure, a handheld device called a...
Computed Tomography
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Continuous -time Fourier Transform
The Fourier series is instrumental in representing periodic functions, offering a powerful method to decompose such functions into a sum of sinusoids. This technique, however, necessitates modification when applied to nonperiodic functions. Consider a pulse-train waveform consisting of a series of rectangular pulses. When these pulses have a finite period, they can be accurately represented by a Fourier series. Yet, as the period approaches infinity, resulting in a single, isolated pulse, the...
Imaging Studies II: Ultrasonography
IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
