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Updated: Jul 7, 2026

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A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
[An 83-year-old woman with coma and severe hypernatremia]
Trond Engjom1, Odd Kildahl-Andersen
1Medisinsk avdeling, Hålogalandssykehuset Harstad, 9480 Harstad. trond.engjom@helse-bergen.no
Summary
Salt intoxication can cause severe hypernatremia, particularly in vulnerable populations. Prompt treatment with diuretics and fluid replacement is crucial, though optimal strategies remain debated.
Area of Science:
- Nephrology
- Internal Medicine
- Geriatrics
Background:
- Hypernatremia from salt intoxication is a rare but serious condition.
- It disproportionately affects pediatric patients and individuals with cognitive impairments.
- The condition carries a high mortality rate and a poor prognosis.
Observation:
- An elderly, demented female patient presented with coma and critically elevated serum sodium levels (223 mmol/L).
- Literature review on salt intoxication-induced hypernatremia was conducted.
Findings:
- Diagnosis of salt intoxication-induced hypernatremia was confirmed by elevated serum and urine sodium, alongside normovolemia and normal diuresis.
- The patient unfortunately passed away within hours of admission.
Implications:
- Management involves promoting diuresis with loop diuretics and replacing fluid losses.
- Hemodialysis is a viable alternative for inadequate diuresis.
- Optimal fluid replacement strategies for this condition require further research and consensus.
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