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Cutaneous herpes simplex virus infections.

D M Arbesfeld1, I Thomas

  • 1University of Medicine and Dentistry of New Jersey, Medical School, Newark.

American Family Physician
|May 1, 1991
PubMed
Summary
This summary is machine-generated.

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Herpes simplex virus (HSV) infections are common, with varied clinical presentations. Acyclovir is a primary treatment, but resistant cases may need alternatives like phosphonoformate trisodium.

Area of Science:

  • Virology
  • Infectious Diseases
  • Dermatology

Background:

  • Herpes simplex virus (HSV) infections represent a significant public health concern, affecting millions annually in the United States.
  • Clinical manifestations of HSV infections are diverse, influenced by factors such as infection site, patient age, and immune status.
  • Accurate diagnosis relies on a combination of clinical assessment and laboratory investigations.

Purpose of the Study:

  • To provide an overview of herpes simplex virus infections.
  • To discuss diagnostic approaches for HSV.
  • To outline current and alternative therapeutic strategies for HSV infections.

Main Methods:

  • Review of existing literature on HSV epidemiology, clinical presentations, diagnosis, and treatment.

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  • Analysis of common diagnostic methods used in clinical practice.
  • Evaluation of established and emerging antiviral therapies.

    • Main Results:

    • HSV infections exhibit a wide spectrum of clinical forms.
    • Diagnosis is typically established through clinical evaluation supported by laboratory studies.
    • Acyclovir remains the first-line treatment for most HSV infections.

    Conclusions:

    • Herpes simplex virus infections are highly prevalent and clinically variable.
    • Prompt diagnosis and appropriate treatment are crucial for managing HSV.
    • While acyclovir is effective, alternative agents are necessary for managing acyclovir-resistant HSV infections.